We decode the genetic and epigenetic mechanisms underlying complex diseases — with a special focus on immune-related or chronic conditions — by integrating large-scale multi-omics data with advanced computational methods.
The Genomic Medicine Lab integrates genomics and other multiomics (epigenomics, transcriptomics, proteomics, and metagenomics) to discover novel regulatory elements and therapeutic targets for complex human diseases.
Integrating data across the genome, epigenome, transcriptome, proteome, and microbiome — spanning bulk, single-cell, and spatial resolution — to map how regulation drives disease.
Linking complex-trait variants to regulatory elements and their target genes to reveal the biology behind disease risk.
Studying how genetic regulation drives disease across a broad range of conditions — from cancer and autoimmune disease to neurodevelopmental, neuropsychiatric, and infectious disorders.